The Non-Healing Wound: An Early Clue to Calciphylaxis
Main Article Content
Keywords
calciphylaxis, calcification
Abstract
Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is a rare disease that presents as painful, necrotic lesions. While calciphylaxis is most commonly associated with renal insufficiency, calciphylaxis can occur in those without renal impairment. A case of non-uremic calciphylaxis occurring at a below-knee amputation site presenting as a single non-healing wound is provided; this presentation stands in stark contrast to the multiple, exquisitely painful lesions that are typical of calciphylaxis.
References
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2. Lum K, Gardner J 2nd, Dao H Jr. A case of nonuremic calciphylaxis of the penis responding to sodium thiosulfate therapy. JAAD Case Rep. 2023;38:4-7. Published 2023 Jun 1. doi:10.1016/j.jdcr.2023.05.030
3. Zulauf EE, Connors JC, Hardy MA. Manifestation of Nonuremic Calciphylaxis in the Extremities: Case Report and Review. J Foot Ankle Surg. 2022;61(5):e41-e47. doi:10.1053/j.jfas.2021.10.024
4. Swoboda L. Clinical management of nonuremic calcific arteriolopathy: a report of three cases. Wounds. 2023;35(9):E275-E281. doi:10.25270/wnds/23050
5. Wen W, Portales-Castillo I, Seethapathy R, et al. Intravenous Sodium Thiosulphate for Calciphylaxis of Chronic Kidney Disease: A Systematic Review and Meta-analysis. JAMA Netw Open. 2023;6(4):e2310068. doi:10.1001/jamanetworkopen.2023.10068