A Case Report of a Primary Cutaneous Adenoid Carcinoma: A Diagnostic and Management Challenge
Main Article Content
Keywords
adenoid cystic carcinoma, surgical margins, chemotherapy
Abstract
Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare glandular neoplasm that mimics benign lesions both clinically and histologically making it a diagnostic challenge. Although indolent, ACC has potential for local regional and distant metastasis and even after surgical excision, there is a high recurrence rate. This report outlines a case of a PPACC and reviews current therapeutic approaches.
References
1. Dillon PM, Chakraborty S, Moskaluk CA, Joshi PJ, Thomas CY. Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials. Head Neck. 2016;38(4):620-627.
2. Xu YG, Hinshaw M, Longley BJ, Ilyas H, Snow SN. Cutaneous adenoid cystic carcinoma with perineural invasion treated by mohs micrographic surgery-a case report with literature review. J Oncol. 2010;2010:469049.
3. Naylor E, Sarkar P, Perlis CS, Giri D, Gnepp DR, Robinson-Bostom L. Primary cutaneous adenoid cystic carcinoma. J Am Acad Dermatol. 2008;58(4):636-641.
4. Ramakrishna R, Raza SM, Kupferman M, Hanna E, DeMonte F. Adenoid cystic carcinoma of the skull base: results with an aggressive multidisciplinary approach. J Neurosurg. 2016;124(1):115-121.
5. Tiwari R, Agarwal S, Sharma M, Gaba S. Primary cutaneous adenoid cystic carcinoma: A clinical and histopathological mimic: A case report. Oral and Maxillofacial Surgery Cases. 2018;4(4):175-179. doi:10.1016/j.omsc.2018.09.002
6. Jaso J, Malhotra R. Adenoid cystic carcinoma. Arch Pathol Lab Med. 2011;135(4):511-515.
7. Cacchi C, Persechino S, Fidanza L, Bartolazzi A. A primary cutaneous adenoid-cystic carcinoma in a young woman. Differential diagnosis and clinical implications. Rare Tumors. 2011;3(1):7-9. doi:10.4081/rt.2011.e3
8. Chae YK, Chung SY, Davis AA, et al. Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling. Oncotarget. 2015;6(35):37117-37134.
2. Xu YG, Hinshaw M, Longley BJ, Ilyas H, Snow SN. Cutaneous adenoid cystic carcinoma with perineural invasion treated by mohs micrographic surgery-a case report with literature review. J Oncol. 2010;2010:469049.
3. Naylor E, Sarkar P, Perlis CS, Giri D, Gnepp DR, Robinson-Bostom L. Primary cutaneous adenoid cystic carcinoma. J Am Acad Dermatol. 2008;58(4):636-641.
4. Ramakrishna R, Raza SM, Kupferman M, Hanna E, DeMonte F. Adenoid cystic carcinoma of the skull base: results with an aggressive multidisciplinary approach. J Neurosurg. 2016;124(1):115-121.
5. Tiwari R, Agarwal S, Sharma M, Gaba S. Primary cutaneous adenoid cystic carcinoma: A clinical and histopathological mimic: A case report. Oral and Maxillofacial Surgery Cases. 2018;4(4):175-179. doi:10.1016/j.omsc.2018.09.002
6. Jaso J, Malhotra R. Adenoid cystic carcinoma. Arch Pathol Lab Med. 2011;135(4):511-515.
7. Cacchi C, Persechino S, Fidanza L, Bartolazzi A. A primary cutaneous adenoid-cystic carcinoma in a young woman. Differential diagnosis and clinical implications. Rare Tumors. 2011;3(1):7-9. doi:10.4081/rt.2011.e3
8. Chae YK, Chung SY, Davis AA, et al. Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling. Oncotarget. 2015;6(35):37117-37134.