SKIN The Journal of Cutaneous Medicine

About the Journal

SKIN is a peer-reviewed, open access, online only journal dedicated to providing free access globally to disseminate dermatological knowledge. Authors retain copyright in their articles, licensing publication of their content through use of Creative Commons CCBY license. The journal does not charge fees, and is supported by the National Society for Cutaneous Medicine.

Current Issue

Vol. 8 No. 6 (2024): November 2024 Issue

Published: 2024-11-18

ISSUE HIGHLIGHTS

In-Depth Reviews

Allergens Causing Allergic Contact Dermatitis in Cosmetic Products: A Systematic Review

Trya Oktaviani, Suci Widhiati, Harijono Kariosentono , Muhammad Eko Irawanto, Triasari Oktavriana

Page 1908-1919

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A Systematic Review of the Association of Elastosis Perforans Serpiginosa and Congenital Disorders

Carolyn Heckman, Elizabeth Flatley, Rucha Janodia

Page 1920-1933

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Tissue-Engineered Skin Substitutes for Use in Clinical Dermatological Practice

Kaitlyn Ramsay, Katarina Laketic, Maria Hangad, Samiha Mohsen

Page 1934-1945

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Original Research

How Automation in Electronic Medical Records Can Lead to Errors in Dermatology

Kaycee Nguyen, Clay J. Cockerell MD, MBA, JD

Page 1946-1951

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Effects of Mineral and Almond Oil Administration on Transepidermal Water Loss and Skin Acidity in Chronic Renal Failure Patients Undergoing Hemodialysis

Trya Oktaviani, Endra Yustin Ellistasari, Benedikta Lauda Anandita

Page 1952-1958

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Medical Education in Dermatology

Imposter Syndrome in Dermatology

Michael Brennan, Audrey Fotouhi, Steven Daveluy

Page 1959-1965

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Publication Outcomes of Abstracts Presented at the 2020 Society for Investigative Dermatology Annual Meeting

Madeline Brown, Priscilla Mammen, Dakarai Dunbar, Albert Zhou, Hao Feng

Page 1966-1970

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Research Letters

Investigating the Impact of Financial Sponsorship in Dermatology Research

Umayr Shaikh, Ayushya Ajmani, David Makaj, Payal Shah

Page 1971-1973

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Brief Articles

A Case of Cutaneous Squamous Cell Carcinoma Treated with Neoadjuvant Cemiplimab

Iraj Hasan, Mary Garland-Kledzik

Page 1974-1977

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Eosinophil-rich Linear IgA Bullous Dermatosis: A Case Report of a Rare Entity

Celter Odango, MS, Grace Im, MS, Abigail C. Wills, MD, Sarah Gradecki, MD, Richard H Flowers, MD

Page 1978-1980

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Palmoplantar Psoriasis Treatment with Topical Roflumilast 0.3%

Diego Ruiz Dasilva

Page 1981-1983

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Successful Treatment of Perioral Dermatitis with Upadacitinib

Anya Patel, William Lau, Mark Lebwohl

Page 1984-1986

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Pityriasis Rubra Pilaris, Refractory to IL-17A Inhibition, with Rapid Improvement Following IL-17A/IL-17F Blockade by Bimekizumab

Jeremy Orloff, Grayson Domzalski, Shivkar Amara, Mark Lebwohl

Page 1987-1992

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Multiple Injection Site Reactions after Treatment with Different Biologics for Psoriasis and Psoriatic Arthritis

Grayson Domzalski, William C. Lau, BA, Rebecca Barzi, RN, Rachel L. Miller, MD, Mark G. Lebwohl, MD

Page 1993-1996

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The Treatment of Lichen Sclerosus with Topical Roflumilast 0.3% Case Study

Erik Domingues

Page 1997-2000

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Sclerotic Fibroma in a Patient with Birt-Hogg-Dubé Syndrome

Pelin Sagut, Nicholas Strat, Elston Dirk

Page 2001-2005

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Concomitant Eruptive Squamous Atypia and Bullous Drug Eruption Associated with Pembrolizumab

Kevin Yang, MD, Hoang Ho-Pham, MD, Jordan Beam, BS, Lauren Kole, MD

Page 2006-2010

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The Non-Healing Wound: An Early Clue to Calciphylaxis

Carlie Reeves

Page 2011-2015

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A Case of Zoonotic Domestically Acquired Hansen Disease (Leprosy) in the State of Georgia

Daniel Nicolle, Jodi Ganz, Melinda Mohr

Page 2016-2020

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Utilizing Upadacitinib for the Management of Hailey-Hailey Disease

Hayden Y. K. Fung, William Lau, Mark Lebwohl

Page 2021-2024

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Carpal Tunnel Corticosteroid Injection Treatment of Nail Lichen Planus

Miranda Lee-Foltz, Payal Shah, Denise Aaron

Page 2025-2028

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Photosensitivity Dermatitis associated with the Moderna Booster Vaccination

Hadley Hudson, Milaan Shah

Page 2029-2033

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SKINmages: Clinical Images in Dermatology

Cutaneous Manifestations of the Hemiscorpius lepturus Stings

Hossein Sanaei-Zadeh

Page 2034-2036

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The Penile Lymphatic Malformation Causing Urinary Obstruction

Khalid Al Aboud, Ahmad Al Aboud, Daifullah Al Aboud

Page 2037-2039

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Pediatric Viscerocutaneous Loxoscelism: A Web of Clinical Challenges

Meagan Olivet, James Clayton Parker, Tiffany Mayo

Page 2040-2041

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Poster Presentations from FC24 Dermatology Conference®: Psoriasis

Recalcitrant Scalp Psoriasis Successfully Treated with Once-Daily Roflumilast Cream 0.3%

ERIK DOMINGUES

Page s417

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Ixekizumab Improves Nail, Scalp, and Skin Response and Quality of Life Independent of Baseline Psoriasis Severity: Results From the Psoriasis in Special Areas (PSoSA) Study

Shari Lipner, Cindy Owen, Neil Korman, William Malatestinic, Meghan Feely McDonald, Mwangi James Murage, Ali Sheikhi Mehrabadi, Joseph Merola

Page s418

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Deucravacitinib in Plaque Psoriasis: Laboratory Parameters Through 4 Years of Treatment in the Phase 3 POETYK PSO-1, PSO-2, and LTE Trials

Neil J. Korman, Thierry Passeron, Yukari Okubo, Jerry Bagel, Richard B. Warren, Lynda Spelman, Kevin Winthrop, Kim Hoyt, Thomas Scharnitz, Subhashis Banerjee, Diamant Thaçi, Mona Shahriari, Linda Stein Gold

Page s419

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Deucravacitinib, an Oral Selective Tyrosine Kinase 2 (TYK2) Inhibitor, in Patients with Moderate to Severe Scalp Psoriasis: Efficacy and Safety Results of a Phase 3b/4, Multicenter, Randomized, Double-blinded, Placebo-controlled Trial (PSORIATYK SCALP)

Kristina Callis Duffin, Christopher E. M. Griffiths, Matthias Hoffmann, Andrew Blauvelt, Eugene Balagula, Andrew Napoli, Ying-Ming Jou, Rachel Dyme, Virginia Hala, Andreas Pinter, Mark Lebwohl

Page s420

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Real-World Achievement of Skin Clearance Targets and Improved Quality of Life With Risankizumab in Psoriasis Patients With Moderate Skin Involvement (BSA ≥ 3–10%)

Bruce Strober, Manish Patel, Mark I Kaldas, Greg St John, Vishvas Garg, Adam P Sima, Thomas Eckmann, Alicia Beeghly, April Armstrong

Page s421

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Deucravacitinib Long-term Efficacy Through 4 Years in Week 16 Placebo Crossover Patients in the Phase 3 POETYK PSO-1, PSO-2, and LTE Program

Mark Lebwohl, Richard B. Warren, Shinichi Imafuku, Jerry Bagel, April W. Armstrong, Thierry Passeron, Subhashis Banerjee, Matthew J. Colombo, Thomas Scharnitz, Kim Hoyt, Diamant Thaçi, Andrew Blauvelt

Page s422

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Deucravacitinib in Plaque Psoriasis: 4-year Safety and Efficacy Results from the Phase 3 POETYK PSO-1, PSO-2, and LTE Trials

April W. Armstrong, Mark Lebwohl, Richard B. Warren, Howard Sofen, Akimichi Morita, Shinichi Imafuku, Mamitaro Ohtsuki, Lynda Spelman, Thierry Passeron, Kim A. Papp, Matthew J. Colombo, John Vaile, Eleni Vritzali, Kim Hoyt, Carolin Daamen, Subhashis Banerjee, Bruce Strober, Diamant Thaçi, Andrew Blauvelt

Page s423

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Real-world Patient Use and Perception, Satisfaction, and Adherence with a Calcipotriol and Betamethasone Dipropionate PAD-cream for the Treatment of Plaque Psoriasis

José Luis López Estebaranz, Hjalmar Kurzen, Marta Menendez, Giulia Greta Dradi, Jordi Galvan

Page s424

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Deucravacitinib, an Oral, Selective, Allosteric Tyrosine Kinase 2 (TYK2) Inhibitor, in Patients With Moderate to Severe Scalp Psoriasis: Improvement in Scalp-Related Quality of Life and Symptoms in the Phase 3b/4 Multicenter, Randomized, Double-Blinded, Placebo-Controlled PSORIATYK SCALP Trial

Steven R. Feldman, Jerry Bagel, Matthias Hoffmann, Andrew Napoli, Chun-Yen Cheng, Rachel Dyme, Eugene Balagula, Yichen Zhong, Steven E. Kempers, Christopher E. M. Griffiths

Page s425

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Treatments Used Among Patients with Psoriasis: A First Look at a New Patient-Centered Psoriasis Registry

Alexis Ogdie, Joel Gelfand, Laetitia N’Dri, Ying Wu, Thomas Scharnitz, Kaleb Michaud

Page 10.25251/skin.8.supp.426

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Provider Burden Associated With Apremilast Adverse Events

Lana Schmidt, Ying Wu, Vardhaman Patel, Danielle Gentile, Djibril Liassou, Jason Sharpe, Courtney Omary, Monica Ahlquist, Bruce Feinberg

Page s427

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Deucravacitinib in Moderate to Severe Plaque Psoriasis: Comorbidities and Use of Prior and Concomitant Medication in Patients Enrolled in the Phase 3 POETYK PSO-1 and PSO-2 Trials

Joseph F. Merola, Alice B. Gottlieb, Nehal N. Mehta, Matthew J. Colombo, Monica Elias, Francesco De Leonardis, Ying-Ming Jou, Neil J. Korman

Page s428

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Efficacy of Deucravacitinib in Plaque Psoriasis Across a Range of Body Surface Area Involvement: Post hoc Analysis of the Randomized, Double-Blinded, Placebo-Controlled, Phase 3b/4 PSORIATYK SCALP Trial

Andrew Blauvelt, Diamant Thaçi, David M. Pariser, Andrew Napoli, Eugene Balagula, Chun-Yen Cheng, Rachel Dyme, Linda Stein Gold, Mark Lebwohl

Page s429

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Efficacy of Deucravacitinib in Moderate to Severe Scalp Psoriasis: Analysis of Complete Clearance of Scalp Disease and Symptoms

Linda Stein Gold, Andrew Blauvelt, Leon Kircik, Andrew Napoli, Chun-Yen Cheng, Rachel Dyme, Eugene Balagula, Jerry Bagel, Mark Lebwohl

Page s430

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Bimekizumab Efficacy and Safety Over 48 Weeks in US and Canadian Patients with Psoriasis who had a Treatment Interruption After 3 Years of Treatment: Results from BE RADIANT

Mark Lebwohl, Kim Papp, Benjamin Ehst, Mark Lomaga, Phoebe Rich, Bruce Strober, April Armstrong, José M. López Pinto, Markus Kaspar, Delphine Deherder, Maggie Wang, Ronald Vender

Page s431

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Bimekizumab 4-year Efficacy in High-impact Areas in Moderate to Severe Plaque Psoriasis: Pooled Results from BE BRIGHT

Joseph F. Merola, Alice B. Gottlieb, Jennifer Soung, Philip Hampton, Andreas Pinter, Melinda Gooderham, Akimichi Morita, Sarah Kavanagh, Nancy Cross, Susanne Wiegratz, Carle Paul

Page s432

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Bimekizumab Long-term Efficacy in Patients with Moderate to Severe Plaque Psoriasis After Switching From Adalimumab, Ustekinumab, or Secukinumab: Results from Up to 4 Years of Total Treatment from BE BRIGHT and BE RADIANT

Georgios Kokolakis, George Han, David Pariser, Antonio Costanzo, Richard G. Langley, Rhys Warham, Balint Szilagyi, Bertram Knapp, Mark Lebwohl

Page s433

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Bimekizumab Clinical Efficacy in Important Body Regions and Health-related Quality of Life in Patients with Plaque Psoriasis: Data from Four Phase 3/3b Comparator-controlled Trial Periods

April Armstrong, Boni Elewski, Phoebe Rich, Matthias Augustin, José-Manuel Carrascosa, Ronald Vender, Jérémy Lambert, José M. López Pinto, Bengt Hoepken, Sarah Kavanagh, Luis Puig

Page s434

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Bimekizumab Efficacy and Safety in Patients With Psoriatic Arthritis Who Had Skin and Nail Psoriasis at Baseline: Up to 2-year Results From Two Phase 3 Studies

Diamant Thaçi, Akihiko Asahina, Wolf Henning Boehncke, Alice B. Gottlieb, Mark Lebwohl, Richard B. Warren, Barbara Ink, Rajan Bajracharya, Jason Coarse, Joseph F. Merola

Page s435

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Bimekizumab Safe and Effective Self-administration Using 2 mL Devices by Patients with Moderate to Severe Plaque Psoriasis: Results from Two Multicenter, Randomized, Open-label Studies

Jerry Bagel, Daljit Tatla, Bertram Knapp, Thomas Vaux, Bengt Hoepken, Michael Sebastian

Page s436

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Bimekizumab 4-year Maintenance of Responses in Week 16 Responders with Moderate to Severe Plaque Psoriasis: Results from the BE BRIGHT Open-label Extension Phase 3 Trial

Andrew Blauvelt, Peter Foley, Richard G. Langley, Curdin Conrad, David Rosmarin, Ricardo Romiti, Maggie Wang, Balint Szilagyi, Bengt Hoepken, Richard B. Warren

Page s437

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Brodalumab Versus Ustekinumab in Obese Patients With Moderate-to-Severe Plaque Psoriasis

Sylvia Hsu, April Armstrong, Lawrence Green, Mark Lebwohl, Abby Jacobson

Page s438

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Fixed-Combination Halobetasol Propionate 0.01% and Tazarotene 0.045% Lotion and Halobetasol Propionate 0.01% Lotion for Plaque Psoriasis on Areas With Body Hair: Maintenance of Treatment Effect

George Han, Edward Lain, Linda Stein Gold, Abby Jacobson

Page s439

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Demonstration of the Clinical Utility of a Psoriasis Precision Medicine Tool: Findings from the MATCH Study Show Altered Physician Behavior Leads to Improved Patient Outcomes

Tobin Dickerson, Bruce Strober, Michael Bukhalo, April Armstrong, David Pariser, Leon Kircik, Paul Montgomery, III

Page s440

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Zasocitinib (TAK-279), a Selective, Oral TYK2 Inhibitor, Reduces Body Surface Area Involvement in a Phase 2b Trial in Moderate-to-Severe Plaque Psoriasis

Vivian Laquer, Leon H. Kircik, Neil Sadick, Jamie Weisman, Jessamyn Blau, Wenwen Zhang, Jonathan Uy, Warren Winkelman, Melinda Gooderham

Page s441

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Evaluation of Changes in Laboratory Parameters from a Phase 2b Trial of Zasocitinib (TAK-279), an Oral, Selective TYK2 Inhibitor, in Patients with Moderate-to-Severe Plaque Psoriasis

Melinda Gooderham, Christopher Bunick, Leon H. Kircik, Charles Lynde, Lone Skov, Jessamyn Blau, Wenwen Zhang, Jonathan Uy, Warren Winkelman, Diamant Thaçi

Page s442

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Real-World Switch Rates of Risankizumab and Other Biologics in Psoriasis Patients With Psoriatic Arthritis

April W. Armstrong, Manish Patel, Zachary R. Babcock, Chao Li, Jashin J. Wu

Page s443

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Psoriatic Arthritis

Maintenance of Response to Risankizumab in Patients With Psoriatic Arthritis: A 4-Year Analysis of the KEEPsAKE 1 and 2 Trials

Andrew Östör, Lila Glotfelty, Jonathon Rocco, Cuiyong Yue, Joseph F Merola

Page s444

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Long-Term Efficacy and Safety of Risankizumab for csDMARD-IR Patients With Active Psoriatic Arthritis: 196-Week Results From the KEEPsAKE 1 Trial

Frank Behrens, Mauro Keiserman, Kim Papp, Douglas White, Angela Crowley, Tshepiso Madihlaba, Thomas Iyile, Kyle Carter, Ahmed Soliman, Doug Ashley, Lily Glotfelty

Page s445

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Long-Term Efficacy and Safety of Risankizumab for Active Psoriatic Arthritis: 196-Week Results From the KEEPsAKE 2 Trial

Andrew Östör, Filip Van den Bosch, Kim Papp, Cecilia Asnal, Ricardo Blanco, Jacob Aelion, Ana Biljan, Jonathon Rocco, Fang Liu, Ahmed Soliman, Doug Ashley, Lila Glotfelty, Alan Kivitz

Page s446

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Retrospective Analysis of the Impact of Screening for Psoriatic Arthritis (PsA) with the Psoriasis Epidemiology Screening Tool (PEST) in Clinical Dermatology Practice

Lawrence Rasouliyan, Uche Ndefo, Amanda Mummert, Amanda Althoff, Robert Low

Page s447

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Atopic Dermatitis

Utilization and Duration of Systemic Corticosteroid Exposure in Atopic Dermatitis Patients After the Introduction of Advanced Therapies: A Population-Based Study From the United States

Christopher Bunick, Ruth Ann Vleugels, Mark Lebwohl, Ayman Grada, Emma Xiaomeng Yue, Lani Wegrzyn, Elvira D'Andrea

Page s448

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Long-Term Maintenance of Optimal Treatment Targets for Skin and Itch Outcomes With Upadacitinib in Moderate-to-Severe Atopic Dermatitis: 140-Week Results From the Phase 3 Measure Up 1 and 2 Studies

Naiem T Issa, Raj Chovatiya, Jordan Talia, Tiago Torres, Kilian Eyerich, Brian M Calimlim, Yang Yang, Alena Pechonkina, Alvaro Moreira, Ayman Grada, Christopher G Bunick

Page s449

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Real-World Effectiveness of Upadacitinib in Moderate‑to‑Severe Atopic Dermatitis (AD): Results From Longitudinal Analyses of the CorEvitas AD Registry

Jonathan I. Silverberg, Melinda Gooderham, Christopher G. Bunick, Brian Calimlim, Ayman Grada, Yolanda Muñoz Maldonado, Alvin Li, Nicole Fergestrom, Eric Simpson

Page s450

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Switching from Dupilumab to Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab: Efficacy and Safety Results from the Phase 3b/4 LEVEL UP Study

Christopher Bunick, Nina Magnolo, Angela Moore, Gao Xinghua, Charles Lynde, Nadia Ibrahim, Ayman Grada, Gweneth Levy, Brian Calimlim, Xiaoqiang Wu, Yolanda Armendariz, Kilian Eyerich

Page s451

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Optimized Second-Generation IL-4Rα Inhibition: Structural and Molecular Dynamics Properties of Rademikibart Fab-IL-4Rα Complex

Yuanjun Shi, Minh Ho, Haote Li, Raul Collazo, Christopher Bunick

Page s452

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Efficacy and Safety of Ruxolitinib Cream by Anatomic Region in Children Aged 2 to 11 Years With Atopic Dermatitis: Results From TRuE-AD3

Dareen Siri, Amy Paller, April Armstrong, Linda Stein Gold, Howard Kallender, Daniel Sturm, Haobo Ren, Lawrence Eichenfield

Page s453

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Drying of Opzelura® (Ruxolitinib) Cream 1.5%: Implications for Clinical and Real-World Use

Haydar Abdalghafor, Janel Torsiello, Daniel Sturm, Adnan Nasir, Russell Elliott, Ahmad Naim

Page s454

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Association of Ruxolitinib Cream Initiation With Continued Reduction in Use of Other Topical Treatments, Oral Corticosteroids, and Biologics for Atopic Dermatitis

Jinan Liu, Karishma Desai, Chia-Chen Teng, Grace Stockbower, Peter Chen, Vincent Willey, Daniel Sturm

Page s455

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Half-life-extended Monoclonal Antibody APG777 for Atopic Dermatitis: Design of the Phase 2 APEX Study

Emma Guttman-Yassky, Andrew Blauvelt, Melinda Gooderham, Kenji Kabashima, Marilia Oliveira, Li Xie, Angela Wilson, Carl Dambkowski, Kristine Nograles, Jonathan Silverberg

Page s456

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Dupilumab Demonstrates a Higher Likelihood of Achieving Improvements in Signs, Symptoms, and Quality of Life vs. Tralokinumab at Week 16: Results from a Bucher Indirect Treatment Comparison

Yann Cabon, Boya Chandrasekhar, Chien-chia Chuang, Zhixiao Wang, Ana Rossi, Kerry Noonan, Mike Bastian

Page s457

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Patient and Parent/Caregiver Satisfaction with Efficacy and Cosmetic Elegance of Tapinarof Cream 1% Once Daily in a Long-term Extension Trial in Adults and Children Down to Age 2 Years with Atopic Dermatitis

Adelaide A. Hebert, James Del Rosso, Sandra Marchese Johnson, Lawrence J. Green, Sarah Serrao, Philip M. Brown, David S. Rubenstein, Anna Tallman

Page s458

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Achievement of No-to-minimal Itch and Sleep Improvement with Tapinarof Cream 1% Once Daily in Two Pivotal Phase 3 Trials in Adults and Children Down to 2 Years of Age with Atopic Dermatitis

Eric Simpson, Dareen D. Siri, Raj Chovatiya, Mona Shahriari, Autumn F. Burnette, Brittany G. Craiglow, Philip M. Brown, Anna Tallman

Page s459

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Skin Clearance, Treatment Response Off-therapy, and Safety of Tapinarof Cream 1% Once Daily: Results from ADORING 3, a 48-week Phase 3 Trial in Adults and Children Down to 2 Years of Age with Atopic Dermatitis

Robert Bissonnette, Linda Stein Gold, Leon Kircik, Eric Simpson, Lawrence F. Eichenfield, John Browning, Adelaide A. Hebert, Andrew F. Alexis, Weily Soong, Stephen C. Piscitelli, Anna Tallman, David S. Rubenstein, Philip M. Brown, Jonathan I. Silverberg

Page s460

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Why Do Optimal Targets for Itch and Skin Clearance Matter in Atopic Dermatitis Treatment? Insights from TARGET-DERM AD Registry

Jonathan I. Silverberg, Christopher G. Bunick, Brian M. Calimlim, Ayman Grada, Keith D. Knapp, Breda Munoz, Julie M. Crawford, Chibuzo Obi, Amy S. Paller

Page s461

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Persistent Inadequate Disease Control and Therapeutic Inertia in Moderate-to-Severe Atopic Dermatitis: A 12-month Longitudinal Analysis of Real-world Outcomes from the TARGET-DERM AD registry

Lawrence F. Eichenfield, Ayman Grada, Keith Knapp, Breda Munoz, Julie M. Crawford, Jonthan I. Silverberg

Page s462

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Impact of Therapeutic Inertia on Patient-Reported Outcomes in Moderate-to-Severe Atopic Dermatitis: A 12-Month Longitudinal Study from the TARGET-DERM AD Registry

Brenda Simpson, Ayman Grada, Keith Knapp, Breda Munoz, Julie M. Crawford, Jonathan I. Silverberg

Page s463

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Alopecia

Differentiating between Central Centrifugal Cicatricial Alopecia, Traction Alopecia, and Alopecia Areata in Black Patients: Photographic Examples from a Clinical Trial

Amy McMicheal, Susan Taylor, Valerie Callender, Tiffany Mayo, Susan Ball, Fionn McSwiney, Najwa Somani, Chesanna Kindred

Page s464

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Distribution of SALT Scores with Ritlecitinib Treatment up to 24 months from the ALLEGRO Phase 2b/3 and Long-Term Phase 3 Clinical Studies in Alopecia Areata

Ziad Reguiai, Leila Asfour, Delphine Staumont-Sallé, Ángela Hermosa-Gelbard, Andrea Sechi, Dalia Wajsbrot, Rahmat Adejumo, Deborah Woodworth, Alexandre Lejeune

Page s465

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Characterizing Lipid Changes and Use of Lipid-Lowering Medications in Patients With Alopecia Areata Treated With Baricitinib: Integrated Results From the BRAVE-AA1 and -AA2 Clinical Trials

Ruth Ann Vleugals, Arash Mostaghimi, Rodney Sinclair, Bianca Maria Piraccini, Angelina Sontag, Najwa Somani, Karen Denning, Ayush Srivastava, Brett King

Page s466

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Patient Profile and Treatment Characteristics of Early Ritlecitinib Initiators in the US

Samantha K. Kurosky, Liza Takiya, Kent Hanson, Griffith Bell, Yi-Chien Lee, Genevieve Gauthier

Page s467

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Efficacy of Ritlecitinib in Patients with Alopecia Areata by Extent of Hair Loss: Results from the Phase 2b/3 and Phase 3 ALLEGRO Clinical Trials

Arash Mostaghimi, Cheshana Kindred, Pedro Herranz Pinto, Masato Mizuashi, Dalia Wajsbrot, Rahmat Adejumo, Helen Tran, Liza Takiya

Page s468

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Race and Ethnicity Sub-Groups of Alopecia Areata Patients have Differing Clinical Characteristics: TARGET-DERM AA

Maria K Hordinsky, Claire C Bristow, Sven G. Richter, Ahmed M. Soliman, Keith Knapp, Breda Munoz, Julie M. Crawford, Amy S. Paller, Shane Chapman, Lara Wine Lee, Natasha A. Mesinkovska, Benjamin N. Unger

Page s469

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Demographics and Disease Characteristics of Patients with Alopecia Areata with Comorbid Atopic Dermatitis, Vitiligo or Anxiety/Depression: TARGET-DERM AA

Natasha A Mesinkovska, Sven G. Richter, Claire C Bristow, Ahmed M Soliman, Julie M Crawford, Keith D Knapp, Breda Munoz, Lara Wine Lee, M. Shane Chapman, Amy S Paller, Benjamin N Ungar, Maria K Hordinsky

Page s470

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Generic vs. Disease-Specific Patient Reported Outcome (PRO) Instruments for Assessing HRQoL Burden Among Patients Diagnosed with Alopecia Areata: Evidence from TARGET-DERM AA

Benjamin N Ungar, Ahmed M. Soliman, Claire C. Bristow, Sven G. Richter, Breda Munoz, Julie M. Crawford, Keith D. Knapp, Natasha A. Mesinkovska

Page s471

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A Novel Nutraceutical Gummy for Hair Regrowth in Women: A Case Series

Annyella Douglas, Leena Ramani, Spencer Hawkins, Matt Leavitt

Page s472

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Hidradenitis Suppurativa

Bimekizumab Efficacy and Safety Through 2 years in Patients with Hidradenitis Suppurativa: Results from the Phase 3 BE HEARD I&II trials and Open-Label Extension BE HEARD EXT

Christos C Zouboulis, Amit Garg, Christopher J. Sayed, Gregor Jemec, Georgios Kokolakis, John R. Ingram, Akimichi Morita, Pratiksha Dokhe, Ingrid Pansar, Robert Rolleri, Christina Crater, Asim Datye, Alexa B. Kimball

Page s473

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Bimekizumab Effect on the Need for Concomitant Rescue Interventions by HiSCR Response Level in Patients with Moderate to Severe Hidradenitis Suppurativa from BE HEARD I&II

Falk G. Bechara, Seth Forman, Amit Garg, Philippe Guillem, Hesel H. van der Zee, Evangelos J. Giamarellos-Bourboulis, Akimichi Morita, Bartosz Lukowski, Robert Rolleri, Pratiksha Dokhe, Nicola Tilt, Iltefat Hamzavi

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Bimekizumab impact on draining tunnels: A dynamic assessment in patients with moderate to severe HS using pooled Week 48 results from BE HEARD I&II

Thrasyvoulos Tzellos, Jennifer Hsiao, Martina Porter, Farida Benhadou, Falk G. Bechara, Melinda Gooderham, Hidetoshi Takahashi, Christos C Zouboulis, Ingrid Pansar, Robert Rolleri, Nicola Tilt, Christopher Sayed

Page s475

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Bimekizumab impact on patient-reported outcomes in patients with moderate to severe hidradenitis suppurativa: Pooled Week 48 results from BE HEARD I&II

Jacek C Szepietowski, Hadar Lev-Tov, Vivian Y. Shi, Sylke Schneider-Burrus, Antonio Costanzo, Koremasa Hayama, Jérémy Lambert, Tom Vaux, Bartosz Lukowski, Robert Rolleri, Alice B Gottlieb

Page s476

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Bimekizumab cumulative clinical benefit in patients with moderate to severe hidradenitis suppurativa through 1 year of the BE HEARD I&II phase 3 trials

Amit Garg, April Armstrong, Howard Sofen, Antonio Martorell-Calatayud, Maurizio Podda, Toshifumi Nomura, Susanne Wiegratz, Jérémy Lambert, Robert Rolleri, Nicola Tilt, Christos C Zouboulis

Page s477

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Barriers and facilitators to quality HS biologic care and outcomes for the Medicaid population across US states

Steven Daveluy, Brindley Brooks, Brent Hazelett, Iltefat Hamzavi, Ginette A. Okoye, Laura Bush, Jasmine I. Espy, Danuta Marchi, Matthew Rudberg, Tae Oh, Stephanie Goldberg

Page s478

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Microwave Energy for Managing Hidradenitis Suppurativa

Nicole Bielecki DMSc, MSPAS, PA-C, Aaron Hoover, MD

Page s479

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Skin Cancer

Results of a Phase 2 Multicenter Study Evaluating the Safety and Tolerability of VP-315, an Investigational Therapy for Basal Cell Carcinoma

Neal Bhatia MD, Jonathan Kantor MD, Lawrence Green MD, Jonathan Weiss MD, Cynthia Willson RN, BSN, Susan Cutler DMD, Jayson Rieger PhD, MBA, David K. Glover ME, PhD, Pamela Rumney RN, CCRC, Thomas F. Haws, Gary Goldenberg MD

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Results of a Phase 2 Multicenter Study to Evaluate the Efficacy of VP-315, an Investigational Therapy for Basal Cell Carcinoma

Jonathan Kantor MD, Neal Bhatia MD, Lawrence Green MD, Jonathan Weiss MD, Kenneth Y. Tsai, MD, PhD, Cynthia Willson RN, BSN, Susan Cutler DMD, Jayson Rieger PhD, MBA, David K. Glover ME, PhD, Pamela Rumney RN, CCRC, Thomas F. Haws, Gary Goldenberg MD

Page s481

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Microwave Energy for Treatment of Superficial and in situ Squamous Cell Carcinoma

Mark S. Nestor, MD, PhD, Angelica Marrero-Perez, MD, Aysham Chaudry, DO, Robert Vanaria

Page s482

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Evaluating the safety and efficacy of aminolevulinic acid 20% topical solution activated by blue light in the treatment of facial cutaneous squamous cell carcinoma in situ

Aysham Chaudry, DO, Angelica Marrero-Perez, MD, Robert J. Vanaria, Vishnu Bhupalam, Mark S. Nestor, MD, PhD

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Expert Consensus-Based Recommendations on the Use of Photodynamic Therapy in Actinic Keratosis Patients

Dr. Vishal A. Patel, Dr. Sarah T. Arron, Dr. Brian Berman, Dr. M. Shane Chapman, Dr. Anokhi Jambusaria-Pahlajani, Dr. George Martin, Dr. Anthony M. Rossi, Dr. Todd Schlesinger, Dr. Nathalie C. Zeitouni, Dr. Neal Bhatia

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Safety and Efficacy of Photodynamic Therapy with ALA 10% Topical Gel Activated by Red Light versus ALA 20% Topical Solution Activated by Blue Light for the Treatment of Actinic Keratosis on the Upper Extremities: A Blinded Randomized Study

Dr. Payvand Kamrani, Dr. Maya Firsowicz, Dr. Misha Zarbafian, Dr. Kavita Darji, Dr. Raheel Zubair, Dr. Lisa Ishii, Dr. Mitchel Goldman, Dr. Monica Boen

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Pilot study utilizing short contact protocols for treatment of actinic keratoses (AK) with ALA gel-red light photodynamic therapy (PDT)

Jessica Johnson, Jackson Hanna, Dr. Amy S. Nowacki, Sanjay Anand, Alan Shen, Dr. Edward Maytin

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Generalized Pustular Psoriasis

Real-world safety of spesolimab in generalized pustular psoriasis: Evidence from an expanded access program in Argentina

María Laura Galimberti, María Lapadula, Rosana Veira, Nichiren Pillai, Rafael Sani Simões, Ana Rodriguez Castelli, Natalia Dominguez, Glenda Vilchez, Lucas Sheridan, Amy Weatherill, Xuemei Ding

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Spesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time in patients switching from conventional systemic treatments: Results from the EFFISAYIL® 2 trial

Joseph Merola, Bruce Strober, Alice Gottlieb, Arash Mostaghimi, Jason Hawkes, Jason Guercio, Ming Tang, Christian Thoma, Mark Lebwohl

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Spesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time in patients with various lengths of disease history: Results from the EFFISAYIL® 2 trial

Arash Mostaghimi, Bruce Strober, Joseph Merola, Alice Gottlieb, Boni Elewski, Jason Guercio, Ming Tang, Christian Thoma, Mark Lebwohl

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Spesolimab increases the percentage of generalized pustular psoriasis (GPP) patients with clear skin over time as measured by the Physician’s Global Assessment for GPP (GPPGA): Results from the EFFISAYIL® 2 trial

Alice Gottlieb, Bruce Strober, Joseph Merola, Arash Mostaghimi, Aaron Farberg, Jason Guercio, Ming Tang, Christian Thoma, Mark Lebwohl

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Spesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time: Results from the EFFISAYIL® 2 trial

Bruce Strober, Joseph Merola, Alice Gottlieb, Arash Mostaghimi, Jennifer Hsiao, Jason Guercio, Ming Tang, Christian Thoma, Mark Lebwohl

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Four-weekly dosing intervals with subcutaneous spesolimab appear to be required for optimal prevention of generalized pustular psoriasis flares: Data from the EFFISAYIL® 2 and EFFISAYIL® ON trials

Diamant Thaci, Akimichi Morita, Bruce Strober, Tiago Torres, Andreas Pinter, Angelo Marzano, James Krueger, Ming Tang, Patrick Hofmann, Christian Thoma, Mark Lebwohl

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Acne & Rosacea

Dermal and Systemic Pharmacokinetics of Oral DFD-29 (minocycline hydrochloride modified release capsules, 40 mg) vs Oral Doxycycline 40 mg in Healthy Subjects

Dr. Adelaide Hebert, Dr. Srinivas Sidgiddi

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Efficacy and Safety of Fixed-Dose Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel in Participants with Moderate-to-Severe Acne: The Patient Journey

Hilary Baldwin, Julie C. Harper, Joshua A Zeichner, Zoe D Draelos, Lawrence F Eichenfield, Michael Gold, Linda Stein Gold, Leon H Kircik, Eric Guenin

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Efficacy and Safety of Fixed-Dose Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel in Black Participants with Moderate-to-Severe Acne

Valerie D Callender, Andrew F Alexis, Neal Bhatia, Julie C Harper, Eric Guenin, Hilary Baldwin

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Antibacterial Activity of Clindamycin/BPO in Combination With Adapalene

Ahmed Gamal, Mohamed Eltoukhi, Ali Elabbasi , James Q Del Rosso, Mahmoud Ghannoum

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Efficacy and Safety of Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel: Post Hoc Analysis by Baseline Disease Severity

Michael Gold, Edward (Ted) Lain, Julie C Harper, Hilary Baldwin, Linda Stein Gold, Eric Guenin

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Miscellaneous

Environmental Impact and Sustainability Associated with the Practice of Dermatology

Robert J. Vanaria, Vishnu Bhupalam, Angelica Marrero-Perez, MD, Aysham Chaudry, DO, Nardin Awad, DO, Mark S. Nestor, MD, PhD

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Pharmacodynamic effects and exploratory efficacy of afimetoran, a TLR7/8 inhibitor, in patients with cutaneous lupus erythematosus

Jasmine Saini, Stanislav Ignatenko, Kristina Chadwick, Lin Zhu, Huynh Yen Thanh Bach, Hazem Karabeber, Michelle Dawes, Melanie Harrison, Leon Carayannopoulos, Gopal Krishna, Fareeda Hosein, Frédéric Baribaud

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