Olive Oil in Dermatology: Bridging Ancient Traditions with Modern Medicine
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Keywords
olive oil, anti-inflammatory properties, mediterranean diet, wound healing, phenolic compounds, atopic dermatitis, psoriasis, complementary medicine
Abstract
Olives, a staple of Mediterranean culture, hold significant historical, spiritual, and cultural importance, particularly in Islamic traditions. This review explores the use of olives and their derivatives in complementary and alternative medicine, focusing on dermatological applications. A systematic literature review using EMBASE and PubMed databases, adhering to PRISMA guidelines, identified 44 articles for inclusion. Olive oil demonstrated effectiveness in reducing erythema, scaling, and pain associated with radiation and contact dermatitis, and in managing symptoms of atopic dermatitis and psoriasis through modulation of inflammatory pathways. It also promoted wound healing, benefiting patients with pressure ulcers, chronic wounds, and burns. Additionally, the Mediterranean diet, rich in olives, was linked to reduced inflammation in conditions like cystic acne and hidradenitis suppurativa. These dermatological benefits are attributed to the antioxidant and anti-inflammatory properties of olive's phenolic compounds. This review highlights olives’ potential in dermatology as a natural, affordable treatment option, encouraging further research into their therapeutic applications.
References
2. Lorite-Fuentes I, Montero-Vilchez T, Arias-Santiago S, Molina-Leyva A. Potential Benefits of the Mediterranean Diet and Physical Activity in Patients with Hidradenitis Suppurativa: A Cross-Sectional Study in a Spanish Population. Nutrients. 2022;14(3):551. doi:10.3390/nu14030551
3. Alnemer F, Aljohani R, Alajlan A, et al. The use of olive oil for skin health in a Saudi population: A cross-sectional study. Dermatol Reports. 2021;14(1):9364. doi:10.4081/dr.2022.9364
4. Hussain Z, Thu HE, Shuid AN, Kesharwani P, Khan S, Hussain F. Phytotherapeutic potential of natural herbal medicines for the treatment of mild-to-severe atopic dermatitis: A review of human clinical studies. Biomed Pharmacother. 2017;93:596-608. doi:10.1016/j.biopha.2017.06.087
5. Al-Waili NS. Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study. Complement Ther Med. 2003;11(4):226-234. doi:10.1016/s0965-2299(03)00120-1
6. Huang WC, Liou CJ, Shen SC, et al. Oleuropein attenuates inflammation and regulates immune responses in a 2,4-dinitrochlorobenzene-induced atopic dermatitis mouse model. Asian Pac J Allergy Immunol. Published online August 22, 2022. doi:10.12932/AP-200122-1309
7. Poljšak N, Kreft S, Kočevar Glavač N. Vegetable butters and oils in skin wound healing: Scientific evidence for new opportunities in dermatology. Phytother Res. 2020;34(2):254-269. doi:10.1002/ptr.6524
8. Michalsen A, Eddin O, Salama A. A case series of the effects of a novel composition of a traditional natural preparation for the treatment of psoriasis. J Tradit Complement Med. 2016;6(4):395-398. doi:10.1016/j.jtcme.2015.08.006
9. Panahi Y, Rastgar N, Zamani A, Sahebkar A. Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial. J Pharmacopuncture. 2020;23(3):173-178. doi:10.3831/KPI.2020.23.3.173
10. Sklenarova R, Allaw M, Perra M, et al. Co-delivering of oleuropein and lentisk oil in phospholipid vesicles as an effective approach to modulate oxidative stress, cytokine secretion and promote skin regeneration. Eur J Pharm Biopharm. 2023;185:126-136. doi:10.1016/j.ejpb.2023.02.018
11. Aparicio-Soto M, Redhu D, Sánchez-Hidalgo M, et al. Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway. Mol Nutr Food Res. 2019;63(21):e1900019. doi:10.1002/mnfr.201900019
12. Chhabra S, Dogra S, Sharma K, Raychaudhuri SK, Raychaudhuri SP. Recent Update on Immunopathogenesis of Psoriasis. Indian J Dermatol. 2022;67(4):360-373. doi:10.4103/ijd.ijd_569_22
13. Santangelo C, Varì R, Scazzocchio B, et al. Anti-inflammatory Activity of Extra Virgin Olive Oil Polyphenols: Which Role in the Prevention and Treatment of Immune-Mediated Inflammatory Diseases? Endocrine, Metabolic & Immune Disorders - Drug Targets. 18(1):36-50.
14. Pazyar N, Yaghoobi R, Rafiee E, Mehrabian A, Feily A. Skin wound healing and phytomedicine: a review. Skin Pharmacol Physiol. 2014;27(6):303-310. doi:10.1159/000357477
15. Wanitphakdeedecha R, Ng JNC, Junsuwan N, et al. Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study. J Cosmet Dermatol. 2020;19(7):1662-1666. doi:10.1111/jocd.13457
16. Ah-Thiane L, Nguyen JM, Khammari A, Dréno B. Lifestyle habits and impact of the Mediterranean diet on facial acne severity in French women: a case-control study. Int J Womens Dermatol. 2022;8(2):e017. doi:10.1097/JW9.0000000000000017
17. Carrara M, Kelly MT, Roso F, Larroque M, Margout D. Potential of Olive Oil Mill Wastewater as a Source of Polyphenols for the Treatment of Skin Disorders: A Review. J Agric Food Chem. 2021;69(26):7268-7284. doi:10.1021/acs.jafc.1c00296
18. Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences. 2018;19(1):70. doi:10.3390/ijms19010070
19. Viola P, Viola M. Virgin olive oil as a fundamental nutritional component and skin protector. Clin Dermatol. 2009;27(2):159-165. doi:10.1016/j.clindermatol.2008.01.008
20. Siegfried E, Glenn E. Use of olive oil for the treatment of seborrheic dermatitis in children. Arch Pediatr Adolesc Med. 2012 Oct;166(10):967. doi: 10.1001/archpediatrics.2012.765. PMID: 22893193.
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Zaryab Alam, Texas A&M University Health Sciences Center
Aasim Jaffri, Albany Medical College
Rahib Islam, LSU Health New Orleans School of Medicine
M Zaid Shami, HCA Florida Aventura Hospital and Medical Center
Hamza Malick, Texas A&M University Health Sciences Center
Aamir Hussain, MedStar Georgetown University Hospital MedStar Washington Hospital Center Internal Medicine Residency Program