A Verrucous Lesion on a Nose in HIV Seropositive Female: A Rare Case Report
Main Article Content
Keywords
Tuberculosis cutis orificialis, Cutaneous TB, Verrucous growth
Abstract
Tuberculosis is a chronic granulomatous infectious disease caused by mycobacterium tuberculosis and mycobacterium bovis. Although commonly affecting lungs, almost all other organ systems may be involved. Cutaneous tuberculosis is one of the most challenging diseases to diagnose. It possesses a wide array of differential diagnosis and is difficult to confirm microbiologically, often leading to delayed diagnosis and treatment. Emergence of resistant strains and the HIV pandemic contribute to distribution of cutaneous tuberculosis worldwide. Clinical findings of cutaneous tuberculosis depend on source of infection and immune status of host. We report an HIV seropositive female presenting with a verrucous fungating growth over nose, which was diagnosed as tuberculosis cutis orificialis likely due to endogenous seeding from pulmonary disease. She was treated with extended anti-tubercular therapy (HRZE) fixed dose combination. The lesion responded remarkably to treatment and resolved completely within 18 months.
References
2. Ganesan A, Kumar G. Scrofuloderma: A rare cutaneous manifestation of tuberculosis. Journal of Indian Academy of Oral Medicine and Radiology. 2017 Jul 1;29(3):223-6.
3. Halim MS, Ahmed SQ, Junaid M, Bashir MR. Tuberculosis verrucosa cutis in a patient with keloid over ear lobule. Case Reports. 2013 Jul 10;2013: bcr2013010294.
4. Anupam V, Tarang G. Incidence of various clinico-morphological variants of cutaneous tuberculosis and HIV concurrence: a study from the Indian subcontinent. (2011): 134-139
5. Jindal SK, Jindal A, Agarwal R. Upper respiratory tract tuberculosis. Tuberculosis and nontuberculous mycobacterial infections. 2017 Jun 1:299-308.
6. Alavi SM, Nashibi R. Nasal tuberculosis in a 56 year old woman. Caspian Journal of Internal Medicine. 2014;5(1):49.
7. Saha K, Mitra M, Saha A, Barma P. Primary nasal tuberculosis following blunt trauma nose. Medical Journal of Dr. DY Patil University. 2014 Jan 1;7(1):50-2.
8. Gharabaghi N, Sedokani A. Chronic Perioral Tuberculosis Skin Lesions in a 21-Year-Old Male. Infection and Drug Resistance. 2020 Sep 25:3273-6.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
Creative Commons Attribution (CC BY): lets others distribute and copy the article, to create extracts, abstracts, and other revised versions, adaptations or derivative works of or from an article (such as a translation), to include in a collective work (such as an anthology), to text or data mine the article, even for commercial purposes, as long as they credit the author(s), do not represent the author as endorsing their adaptation of the article, and do not modify the article in such a way as to damage the author's honor or reputation.
Authors retain copyright in their work and license the publisher to publish the content. The publisher is the National Society for Cutaneous Medicine, with production and publishing support provided by OJS, Open Journal Systems,see https://pkp.sfu.
Prior to January 2022, authors transferred copyright to the National Society for Cutaneous Medicine. However, all articles are freely available to anyone in the world. There are no subscription fees, page charges, or article processing charges.