Cutaneous Type Pemphigus Vulgaris of the Scalp: A Rare Unilesional Presentation
Main Article Content
Keywords
pemphigus, vulgaris, isolated, scalp, mucocutaneous, mucous, membrane, cutaneous, acantholysis, acantholytic, PV, autoimmune, mucus, desmoglein
Abstract
Pemphigus Vulgaris (PV) is the most common subtype of pemphigus, a rare group of autoimmune bullous diseases affecting the skin and mucous membranes. PV can be further subdivided into mucocutaneous and mucosal dominant types, depending on the extent of cutaneous involvement. Almost all cases of PV have mucosal involvement; however, a rare variant of cutaneous-only PV has been reported in the literature. To our knowledge, only two previous accounts of unilesional scalp PV have been reported. We present an unusual case of cutaneous-only PV involving the scalp.
References
2. Carew B, Wagner G. Cutaneous pemphigus vulgaris with absence of desmoglein 1 autoantibodies. An example of the extended desmoglein compensation theory. Australas J Dermatol. 2014;55(4):292-295.
3. Yoshida K, Takae Y, Saito H, et al. Cutaneous type pemphigus vulgaris: A rare clinical phenotype of pemphigus. J Am Acad Dermatol. 2005;52(5):839-845.
4. Rangel J. Pregnancy-Associated "Cutaneous Type" Pemphigus Vulgaris. Perm J. May 2015.
5. Gheisari M, Shahidi-Dadrass M, Nasiri S, Dargah SM, Dadkhahfar S, Abdollahimajd F, Cutaneous-type of Pemphigus Vulgaris, Journal of the American Academy of Dermatology (2020).
6. Oretti G, Giordano D, Di Lella F, Gradoni P, Zendri E, Ferri T. Unilesional pemphigus vulgaris of the scalp after cochlear implantation. Am J Otolaryngol. 2011 Jan-Feb;32(1):80-1.
7. Ferrara G, Massone C, Zalaudek I, Argenziano G. Unilesional pemphigus vulgaris of the scalp. Dermatol Online J. 2009 Oct 15;15(10):9.
8. Sar-Pomian M, Rudnicka L, Olszewska M. The Significance of Scalp Involvement in Pemphigus: A Literature Review. Biomed Res Int. 2018;2018:1-8.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
Creative Commons Attribution (CC BY): lets others distribute and copy the article, to create extracts, abstracts, and other revised versions, adaptations or derivative works of or from an article (such as a translation), to include in a collective work (such as an anthology), to text or data mine the article, even for commercial purposes, as long as they credit the author(s), do not represent the author as endorsing their adaptation of the article, and do not modify the article in such a way as to damage the author's honor or reputation.
Authors retain copyright in their work and license the publisher to publish the content. The publisher is the National Society for Cutaneous Medicine, with production and publishing support provided by OJS, Open Journal Systems,see https://pkp.sfu.
Prior to January 2022, authors transferred copyright to the National Society for Cutaneous Medicine. However, all articles are freely available to anyone in the world. There are no subscription fees, page charges, or article processing charges.
Stefanie Altmann, Orange Park Medical Center
Department of Dermatology
PGY-2 Dermatology Resident