Successful Treatment of Perioral Dermatitis with Upadacitinib

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Anya Patel
William Lau
Mark Lebwohl

Keywords

perioral dermatitis, Janus kinase inhibitor, upadacitinib

Abstract

Perioral dermatitis (POD) is a benign, chronic inflammatory skin condition characterized by small papules, pustules, and erythematous scaly patches around the perioral region. Treatment is not reliably effective, and the condition can be prolonged. We herein report a case of the successful treatment of perioral dermatitis (POD) using upadacitinib. A 45-year-old female with a history of rosacea, presented to the clinic with a 2-3-year history of severely pruritic erythematous papules around the chin and mouth, consistent with POD. Our study demonstrates that Janus kinase inhibitors are a promising therapeutic modality for this condition.


 

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