A Rare Case of Pemphigoid Gestationis
Main Article Content
Keywords
pemphigus, pemphigus gestationis, pemphigoid gestationis, autoimmune blistering disease, pruritus, urticarial plaque, BP180 antibodies, pregnancy dermatose, bullous pemphigus, pregnancy related skin disorder, inflammatory dermatose, dermatitis, autoimmune skin conditions, pregnancy rash
Abstract
Pemphigoid gestationis (PG) is a condition that arises in pregnant women, typically presenting with pruritic and urticarial plaques and/or bullae involving the umbilicus. This report discusses a 36-year-old woman, 26 weeks pregnant, who presented with an intensely pruritic rash that spread from her thighs to her abdomen, forearms, and toe. Physical examination revealed annular pink papules and plaques, notably lacking bullae and sparing the umbilicus. Biopsy and direct immunofluorescence confirmed PG as well as the presence of serum BP180 antibodies. She responded well to clobetasol and cetirizine, and due to preeclampsia delivered preterm. PG is a rare condition that must be considered in pregnant patients promptly in order to avoid complications for both the mother and child.
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