Budget Impact Analysis of Delgocitinib Cream for Moderate to Severe Chronic Hand Eczema in the United States
Main Article Content
Keywords
Budget impact, delgocitinib, Chronic Hand Eczema
References
1. Worm et al. The pan-JAK inhibitor delgocitinib in a cream formulation demonstrates dose response in chronic hand eczema in a 16-week randomized phase IIb trial. Br J Dermatol. 2022; 187(1):42-51.
2. Thyssen et al. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis.
2022;86(5):357-378.
3. Bewley et al. The psychosocial impact of chronic hand eczema - findings from the population-based CHECK (Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden) study. Presented at: ISPOR Europe; November 2024.
4. Fowler et al. Impact of chronic hand dermatitis on quality of life,
work productivity, activity impairment, and medical costs. Journal of the American Academy of Dermatology. 2006;54(3):448-457.
5. Armstrong et al. Economic Burden of Chronic Hand Eczema: A Review. Am J Clin Dermatol. 2022;23(3):287-300.
6. Augustin et al. Cost‐of‐illness of patients with chronic hand eczema in routine care: results from a multicentre study in Germany. British Journal of Dermatology. 2011;165(4):845-851.
7. Molin et al. Health care visits and out-of-pocket costs in people with Chronic Hand Eczema. Presented at: ISPOR; November 2024.
8. FDA. Anzupgo® Prescribing Information. 2025. Accessed August 10 2025.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/219155s000lbl.pdf
9. OECD. Consumer price index (CPI). 2025. Accessed August 10 2025. https://stats.oecd.org/index.aspx?DataSetCode=PRICES_CPI#
10. LEO pharma. US CHECK study. Data on File. 2025.
11. Quaade et al. Prevalence, incidence, and severity of hand eczema in the general population – A systematic review and meta-analysis. Contact Dermatitis. 2021;84(6):361-374.
12. Apfelbacher et al. Chronic hand eczema in Germany: 5‐year follow‐up data from the CARPE registry. Contact Dermatitis. 2019;80(1):45-53.
13. Crane et al. Hand eczema and steroid-refractory chronic hand
eczema in general practice: prevalence and initial treatment. Br J Dermatol. 2017;176(4):955-964.
2. Thyssen et al. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis.
2022;86(5):357-378.
3. Bewley et al. The psychosocial impact of chronic hand eczema - findings from the population-based CHECK (Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden) study. Presented at: ISPOR Europe; November 2024.
4. Fowler et al. Impact of chronic hand dermatitis on quality of life,
work productivity, activity impairment, and medical costs. Journal of the American Academy of Dermatology. 2006;54(3):448-457.
5. Armstrong et al. Economic Burden of Chronic Hand Eczema: A Review. Am J Clin Dermatol. 2022;23(3):287-300.
6. Augustin et al. Cost‐of‐illness of patients with chronic hand eczema in routine care: results from a multicentre study in Germany. British Journal of Dermatology. 2011;165(4):845-851.
7. Molin et al. Health care visits and out-of-pocket costs in people with Chronic Hand Eczema. Presented at: ISPOR; November 2024.
8. FDA. Anzupgo® Prescribing Information. 2025. Accessed August 10 2025.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/219155s000lbl.pdf
9. OECD. Consumer price index (CPI). 2025. Accessed August 10 2025. https://stats.oecd.org/index.aspx?DataSetCode=PRICES_CPI#
10. LEO pharma. US CHECK study. Data on File. 2025.
11. Quaade et al. Prevalence, incidence, and severity of hand eczema in the general population – A systematic review and meta-analysis. Contact Dermatitis. 2021;84(6):361-374.
12. Apfelbacher et al. Chronic hand eczema in Germany: 5‐year follow‐up data from the CARPE registry. Contact Dermatitis. 2019;80(1):45-53.
13. Crane et al. Hand eczema and steroid-refractory chronic hand
eczema in general practice: prevalence and initial treatment. Br J Dermatol. 2017;176(4):955-964.
