Budget Impact Analysis of Delgocitinib Cream for Moderate to Severe Chronic Hand Eczema in the United States

Main Article Content

Jianni Singh-Landa
Aseel Bin Sawad
Yasmin Bappoo
Ben Llewellyn
Megan Barnes
Douglas Maslin
Sanjeev Balu

Keywords

Budget impact, delgocitinib, Chronic Hand Eczema

References

1. Worm et al. The pan-JAK inhibitor delgocitinib in a cream formulation demonstrates dose response in chronic hand eczema in a 16-week randomized phase IIb trial. Br J Dermatol. 2022; 187(1):42-51.

2. Thyssen et al. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis.
2022;86(5):357-378.

3. Bewley et al. The psychosocial impact of chronic hand eczema - findings from the population-based CHECK (Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden) study. Presented at: ISPOR Europe; November 2024.

4. Fowler et al. Impact of chronic hand dermatitis on quality of life,
work productivity, activity impairment, and medical costs. Journal of the American Academy of Dermatology. 2006;54(3):448-457.

5. Armstrong et al. Economic Burden of Chronic Hand Eczema: A Review. Am J Clin Dermatol. 2022;23(3):287-300.

6. Augustin et al. Cost‐of‐illness of patients with chronic hand eczema in routine care: results from a multicentre study in Germany. British Journal of Dermatology. 2011;165(4):845-851.

7. Molin et al. Health care visits and out-of-pocket costs in people with Chronic Hand Eczema. Presented at: ISPOR; November 2024.

8. FDA. Anzupgo® Prescribing Information. 2025. Accessed August 10 2025.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/219155s000lbl.pdf

9. OECD. Consumer price index (CPI). 2025. Accessed August 10 2025. https://stats.oecd.org/index.aspx?DataSetCode=PRICES_CPI#

10. LEO pharma. US CHECK study. Data on File. 2025.

11. Quaade et al. Prevalence, incidence, and severity of hand eczema in the general population – A systematic review and meta-analysis. Contact Dermatitis. 2021;84(6):361-374.

12. Apfelbacher et al. Chronic hand eczema in Germany: 5‐year follow‐up data from the CARPE registry. Contact Dermatitis. 2019;80(1):45-53.

13. Crane et al. Hand eczema and steroid-refractory chronic hand
eczema in general practice: prevalence and initial treatment. Br J Dermatol. 2017;176(4):955-964.

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