Subcutaneous Panniculitis-Like T-Cell Lymphoma: A Case Report

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David Dayi Xiong
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

Brandon Tyler Beal
Department of Dermatology, Cleveland Clinic, OH

Manisha Manmohan
Department of Dermatology, Cleveland Clinic, OH

Maria Georgina Uberti
Departments of Anatomic Pathology and Dermatology, Cleveland Clinic, OH

Kathryn Riley
Department of Dermatology, Cleveland Clinic

Anthony Fernandez
Department of Dermatology, Cleveland Clinic

Keywords

cutaneous T-cell lymphoma, T-cell lymphoma, chemotherapy, cutaneous lymphoma

Abstract

We present a case of a woman diagnosed with subcutaneous panniculitis-like T-cell lymphoma treated with prednisone and methotrexate with sustained symptom remission, suggesting that uncomplicated subcutaneous panniculitis-like T-cell lymphoma can be managed effectively without multiagent chemotherapy or radiation.

References

1. Willemze R, Jansen PM, Cerroni L, et al. Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC Cutaneous Lymphoma Group Study of 83 cases. Blood. 2008;111(2):838-845. doi:10.1182/blood-2007-04-087288

2. Parveen Z, Thompson K. Subcutaneous Panniculitis-like T-Cell Lymphoma: Redefinition of Diagnostic Criteria in the Recent World Health Organization–European Organization for Research and Treatment of Cancer Classification for Cutaneous Lymphomas. Arch Pathol Lab Med. 2009;133(2):303-308. doi:10.1043/1543-2165-133.2.303

3. Swerdlow S, Campo E, Harris N, Jaffe E, Pileri S, Stein H. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, Fourth Edition. Lyon, France: IARC; 2008.

4. Go RS, Wester SM. Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma. Cancer. 2004;101(6):1404-1413. doi:10.1002/cncr.20502

5. Guenova E, Schanz S, Hoetzenecker W, et al. Systemic corticosteroids for subcutaneous panniculitis-like T-cell lymphoma. Br J Dermatol. 2014;171(4):891-894. doi:10.1111/bjd.13053

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Published
Jan 28, 2020
DOI https://doi.org/10.25251/skin.4.1.13

Article Details

How to Cite
[1]
Xiong, D.D., Beal, B.T., Manmohan, M., Uberti, M.G., Riley, K. and Fernandez, A. 2020. Subcutaneous Panniculitis-Like T-Cell Lymphoma: A Case Report. SKIN The Journal of Cutaneous Medicine. 4, 1 (Jan. 2020), 79–81. DOI:https://doi.org/10.25251/skin.4.1.13.
Issue
Vol. 4 No. 1 (2020): January Issue & Poster Presentations (2020 Winter Clinical Dermatology Conference®)
Section
Brief Articles
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