Complete Histologic Response of Regionally Metastatic Melanoma Treated with Intralesional Interleukin 2, Topical Retinoid and Imiquimod

Main Article Content

William Schaffenburg
Walter Reed National Military Medical Center 8901 Wisconsin Ave, Bethesda, MD 20889
http://orcid.org/0000-0001-6906-6890
Joshua Davis
Walter Reed National Military Medical Center Pathology Department

Nicholas Logemann
Dermatology Department, Naval Medical Center San Diego, CA

Meagan Simpson
Dermatology Department, Walter Reed National Military Medical Center, Bethesda, MD

Keywords

Melanoma, Interleukin 2

Abstract

Abstract not available.

References

1. Shi VY, Tran K, Patel F, et al. 100% Complete response rate in patients with cutaneous metastatic melanoma treated with intralesional interleukin (IL)-2, imiquimod, and topical retinoid combination therapy: results of a case series. J Am Acad Dermatol. 2015 Oct;73(4):645-54. doi: 10.1016/j.jaad.2015.06.060. Epub 2015 Aug 7.

2. Miki Garcia M, Ono Y, Martinez S, et al. Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in combination with topical imiquimod and retinoid cream Melanoma Research. 21(3):235–243, JUNE 2011 DOI: 10.1097/CMR.0b013e328345e95e,
PMID: 21464773

3. Green DS, Bodman-Smith AG, Fischer MD. “Phase I/II study of topical imiquimod and intralesional interleukin-2 in the treatment of accessible metastases in malignant melanoma” BJ Derm, 2007 Feb; 156(2): 337-345. doi: https://doi.org/10.1111/j.1365-2133.2006.07664.x

4. Boyman O, Sprent J. The role of interleukin-2 during homeostasis and activation of the immune system. Nat Rev Immunol. 2010(12):180–190. https://doi.org/10.1038/nri3156

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Published
Oct 27, 2020
DOI https://doi.org/10.25251/skin.4.6.14

Article Details

How to Cite
[1]
Schaffenburg, W., Davis, J., Logemann, N. and Simpson, M. 2020. Complete Histologic Response of Regionally Metastatic Melanoma Treated with Intralesional Interleukin 2, Topical Retinoid and Imiquimod. SKIN The Journal of Cutaneous Medicine. 4, 6 (Oct. 2020), 575–578. DOI:https://doi.org/10.25251/skin.4.6.14.
Issue
Vol. 4 No. 6 (2020): November Issue & Poster Presentations (FC20 Dermatology Conference®)
Section
Brief Articles
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