Acquired Congenital Malalignment of the Great Toenails: A Case Series
Main Article Content
Keywords
Congenital malalignment of the great toenail, acquired congenital malalignment of the great toenail, dystrophic disorders, paclitaxel
Abstract
Congenital malalignment of the great toenail is a dystrophic disorder that is characterized by lateral deviation of the nail plates. It is usually present at birth and diagnosed very early in life. Late onset of this condition, often referred to as, “acquired,” is very uncommon. Mechanical stress and repeated microtraumas to the nail can cause complications that can worsen the appearance of the nail and make the condition more obvious in older individuals, however, there are other triggers for this condition as well, such as drugs that can cause nail changes. Properly diagnosing this condition can prevent patients from undergoing unnecessary treatments and also facilitate the efficient initiation of the correct treatment in patients. Here, we discuss 3 cases of acquired congenital malalignment of the great toenail in patients during their 5th, 8th, and 7th decades of life.
References
2. Bolognia JL, Schaffer JV, Cerroni L, Callen JP. Nail Disorders. In: Dermatology. Edinburgh: Elsevier; 2018:1208.
3. Decker A, Scher RK, Avarbock A. Acquired Congenital Malalignment of the Great Toenails. Skin Appendage Disord. 2016;1:147-9.
4. Yang ST, Cheng M, Lee NR, Chang WH, Lee YL, Wang PH. Paclitaxel-related nail toxicity. Taiwan J Obstet Gynecol. 2019;58:709-711.
5. Baran R, Bureau H. Congenital malalignment of the big toenail: a new subtype. Arch Dermatol. 1987;123:437.
6. Batalla A, Curto JR. Congenital malalignment of the great toenail. Report of two cases. Dermatol Online J. 2014;20:21251.
7. Chaniotakis I, Bonitsis N, Stergiopoulou C, Kiorpeliduo D, Bassukas I. Dizygotic twins with congenital malalignment of great toenails: reappraisal of the pathogenesis. J Am Acad Dermatol. 2007;57:711–715.
8. Singal A, Khanna D. Onychomycosis: Diagnosis and management. Indian J Dermatol Venereol Leprol. 2011;77:659-72.
9. Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. J Dtsch Dermatol Ges. 2013;11:309-19.
10. Haneke E. Important malignant and new nail tumors. J Dtsch Dermatol Ges. 2017;15:367-386.
11. Itin PH, Fistarol SK. Ectodermal dysplasias. Am J Med Genet C Semin Med Genet. 2004;131C:45-51.
12. Tunc SE, Ertam I, Pirildar T, Turk T, Ozturk M, Doganavsargil E. Nail changes in connective tissue diseases: do nail changes provide clues for the diagnosis? J Eur Acad Dermatol Venereol. 2007;21:497-503.
13. Kim M, Kang JH, Cho BK, Song CH, Ock SM, Park HJ. Great toenail dystrophy: a single-center experience and review of the literature. Korean J Fam Med. 2015;36:113–120.