Squamous Cell Carcinoma Arising in a Nevus Sebaceus in a 10-Year-Old Male

Main Article Content

Hannah Porter
University of Vermont Medical Center, Division of Dermatology, 111 Colchester Ave, Burlington, VT 05401

Rebecca Lapides
Robert Larner, M.D., College of Medicine at the University of Vermont, 89 Beaumont Ave, Burlington, VT 05405

Keith Morley
University of Vermont Medical Center, Division of Dermatology, 111 Colchester Ave, Burlington, VT 05401

Laura Greene
University of Vermont Medical Center, Department of Pathology and Laboratory Medicine, 111 Colchester Ave, Burlington, VT 05401

Chin Ho
St Lawrence Health System, 6011 US-11, Canton, NY 13617

Keywords

nevus sebaceous, pediatric nevus sebaceous, squamous cell carcinoma, squamous cell carcinoma within nevus sebaceous

Abstract

The patient is a 10-year-old male who presented to a dermatologist regarding a bleeding plaque on the right scalp. The initial pathology report demonstrated an atypical endophytic squamous proliferation with an infiltrative pattern, raising concern for squamous cell carcinoma versus pseudoepitheliomatous hyperplasia. Physical exam showed a painless 4.4 x 1.2 cm elliptical, rough, orange-to-pink plaque with waxy superficial scale on the left forehead. Wide local excision was performed, and pathology confirmed no residual carcinoma. Squamous cell carcinoma arising in a nevus sebaceous in a pediatric patient is exceedingly rare, but as demonstrated by this case, does occur, emphasizing the need for improved guidelines for management to optimize treatment in the pediatric population.

References

1. Taher M, Feibleman C, Bennett R. Squamous Cell Carcinoma Arising in a Nevus Sebaceous of Jadassohn in a 9 Year Old Girl: Treatment using Mohs Micrographic Surgery with Literature Review. Dermatol Surg. 2010;36:1203-1208. [PMID: 20533930].

2. Belhadjali H, Moussa A, Yahia S et al. Simultaneous Occurrence of Two Squamous Cell Carcinomas Within A Nevus Sebaceous of Jadassohn in an 11 Year Old Girl. Pediatr Dermatol. 2009;26:236-237. [PMID: 19419489].

3. Achavanuntakul P, Thanomkitti K. Squamous Cell Carcinoma within a Congenital Nevus Sebaceous: Case Report and Literature Review. Case Rep Dermatol. 2021;13:75-82. [PMID: 33708087;].

4. Idriss MH, Elston DM. Secondary neoplasms associated with nevus sebaceus of Jadassohn: A study of 707 cases. J Am Acad Dermatol. 2014;70:332-337. [PMID: 24268309].

5. Locke ST, Schaffenburg WC, Breedlove JP, Davis Ii DW, Bowden Iii LP, Royer MC. Squamous cell carcinoma with perineural involvement in nevus sebaceus. Cutis. 2019;103:E17-E19. [PMID: 31116824].

6. Simi CM, Rajalakshmi T, Correa M. Clinicopathologic analysis of 21 cases of nevus sebaceus: a retrospective study. Indian J Dermatol Venereol Leprol. 2008;74:625-7. [PMID: 19171988].

Article Sidebar

PDF
Published
Nov 13, 2023
DOI https://doi.org/10.25251/skin.7.6.22

Article Details

How to Cite
[1]
Porter, H., Lapides, R., Morley, K., Greene, L. and Ho, C. 2023. Squamous Cell Carcinoma Arising in a Nevus Sebaceus in a 10-Year-Old Male. SKIN The Journal of Cutaneous Medicine. 7, 6 (Nov. 2023), 1199–1203. DOI:https://doi.org/10.25251/skin.7.6.22.
Issue
Vol. 7 No. 6 (2023): November 2023 Issue
Section
Brief Articles
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

All authors retain copyright in their articles. All articles published open access allowing for immediate free access to the work and permitting any user to read, download, copy, distribute, print, search, or link to the full texts of articles, crawl them for indexing, pass them as data to software or use them for any other lawful purpose. Permitted reuse is defined by  the following user license:
 

Creative Commons Attribution (CC BY): lets others distribute and copy the article, to create extracts, abstracts, and other revised versions, adaptations or derivative works of or from an article (such as a translation), to include in a collective work (such as an anthology), to text or data mine the article, even for commercial purposes, as long as they credit the author(s), do not represent the author as endorsing their adaptation of the article, and do not modify the article in such a way as to damage the author's honor or reputation. 

Authors retain copyright in their work and license the publisher to publish the content. The publisher is the National Society for Cutaneous Medicine, with production and publishing support provided by OJS, Open Journal Systems,see https://pkp.sfu.ca/ojs/.

Prior to January 2022, authors transferred copyright to the National Society for Cutaneous Medicine. However, all articles are freely available to anyone in the world. There are no subscription fees, page charges, or article processing charges.