The Therapeutic Potential of Withania somnifera (Ashwagandha) in Non-Malignant Dermatological Conditions
Main Article Content
Keywords
nutraceutical, nutraceuticals, ashwagandha, hair loss, supplements, withania somnifera, withanolide
Abstract
Introduction: Withania somnifera (WS), or Ashwagandha, is revered for its anti-inflammatory properties. While widely recognized for its systemic health benefits, including immunomodulatory and antioxidant effects, its dermatological applications remain underexplored. This review aims to address this gap by analyzing evidence on WS’s potential mechanisms, therapeutic uses, and limitations in non-malignant skin conditions.
Methods: A literature search was conducted on Ashwagandha using the PubMed, Google scholar, and Scopus databases and the cited literature in articles initially retrieved. A combination of the following keywords were used: Withania somnifera, Ashwagandha, Withaferin, dermatology, skin, hair loss, alopecia. Among the results, 18 articles met the inclusion/exclusion criteria and were included in the review.
Results: Several studies highlight WS’s potential to treat pigmentary disorders, improve skin aging, manage inflammatory skin conditions, promote wound healing, and support hair and scalp health. WS’s phytochemical composition, particularly its withanolides and phenolics, contributes significantly to its therapeutic effects.
Conclusion: WS shows significant potential in dermatology. It offers antioxidant, anti-inflammatory, and adaptogenic benefits and has a strong safety profile. While preliminary evidence is promising, further research is essential to establish its role in dermatology.
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