Achievement of Treat-to-Target Thresholds with Envudeucitinib, a Selective TYK2 Inhibitor, in Moderate-to-Severe Plaque Psoriasis: Results from STRIDE and OLE
Main Article Content
Keywords
next-generation oral, envudeucitinib, ESK-001, Treat-To-Target
References
1. Armstrong AW et al. From the Medical Board of the National Psoriasis Foundation: Treatment targets for plaque psoriasis. J Am Acad Dermatol. 2017;76(2):290-298.
2. Mahil SK et al. Psoriasis treat to target: defining outcomes in psoriasis using data from a realworld, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR). Br J Dermatol. 2020;182(5):1158-1166.
3. Gisondi P et al. Treat-to-Target Approach for the Management of Patients with Moderate-toSevere Plaque Psoriasis: Consensus Recommendations. Dermatol Ther (Heidelb). 2021;11(1):235-252.
4. Golbari NM et al. Psoriasis severity: commonly used clinical thresholds may not adequately convey patient impact. J Eur Acad Dermatol Venereol. 021;35(2):417-421.
5. Blauvelt A et al. Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, doubleblinded, placebo-controlled, dose-ranging phase 2 study. J Am Acad Dermatol. 2025:S0190
9622(25)02466-1.
6. Blauvelt et al. EADV2025 Poster Presentation.
https://www.alumis.com/file.cfm/18/docs/eadv_late_breaker_presentation_final.pd
2. Mahil SK et al. Psoriasis treat to target: defining outcomes in psoriasis using data from a realworld, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR). Br J Dermatol. 2020;182(5):1158-1166.
3. Gisondi P et al. Treat-to-Target Approach for the Management of Patients with Moderate-toSevere Plaque Psoriasis: Consensus Recommendations. Dermatol Ther (Heidelb). 2021;11(1):235-252.
4. Golbari NM et al. Psoriasis severity: commonly used clinical thresholds may not adequately convey patient impact. J Eur Acad Dermatol Venereol. 021;35(2):417-421.
5. Blauvelt A et al. Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, doubleblinded, placebo-controlled, dose-ranging phase 2 study. J Am Acad Dermatol. 2025:S0190
9622(25)02466-1.
6. Blauvelt et al. EADV2025 Poster Presentation.
https://www.alumis.com/file.cfm/18/docs/eadv_late_breaker_presentation_final.pd
