An Evaluation of the Safety and Efficacy of Aminolevulinic Acid Hydrochloride Topical Gel, 10% with Red Light in the Treatment of Facial Cutaneous Squamous Cell Carcinoma in situ
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Keywords
ALA-PDT, aminolevulinic acid, Red light, blue light, Photodynamic therapy, NMSC, non-melanoma skin cancer
Abstract
Cutaneous squamous cell carcinoma in situ (SCCis) is a common skin cancer associated with chronic sun exposure and frequently arises on the face. While surgical excision remains the standard of care, there is growing interest in less invasive options. This study evaluates the safety, tolerability, and efficacy of red-light photodynamic therapy (PDT) with 10% aminolevulinic acid (ALA) topical gel for the treatment of facial SCCis.
References
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3. Nestor MS, Han H, Ceci FM, Lawson A, Gade A. Evaluating the safety and efficacy of aminolevulinic acid 20% topical solution activated by pulsed dye laser and blue light in the treatment of facial cutaneous squamous cell carcinoma in situ. J Cosmet Dermatol. 2023;22(9):2471-2475. doi:10.1111/jocd.15886
4. Nestor MS, Berman B, Patel J, Lawson A. Safety and Efficacy of Aminolevulinic Acid 10% Topical Gel versus Aminolevulinic Acid 20% Topical Solution Followed by Blue-light Photodynamic Therapy for the Treatment of Actinic Keratosis on the Face and Scalp: A Randomized, Double-blind Study. J Clin Aesthet Dermatol. 2019;12(3):32-38.
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